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Regarding hepatosteatosis grading, larger differences were observed in the None (SMD = 0.55) and Grade 3 (SMD = 0.54) categories, whereas Grade 1 (SMD = 0.08) and Grade 2 (SMD = 0.14) were relatively balanced between groups

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Glucagon-like peptide-1 (GLP-1) receptor analogs are drugs that mimic fullness hormone GLP-1 and have been shown to reduce appetite, slow digestion, help stabilize blood sugar levels and impact metabolism

In a higher-BMI subgroup (n532) escalated to the maximum tolerated dose, mean weight reduction reached up to ~30% by week 104